This questionnaire has shown high sensitivity for depression screening in many studies. BDRS exhibited good internal validity and significant correlations with the HAM-D and the MADRS. The mean age of the bipolar group was significantly lower than that of the non-bipolars (P < 0.05). In, ferent from the other items. The sample consisted of 299 subjects admitted to outpatient or inpatient services of 3 psychiatric centers in Tehran, Iran. The present findings suggest that the K-BDRS has good psychometric properties and is a valid and reliable tool for assessing depressive symptoms in patients with bipolar disorder. ve Disorders: A Randomized Clinical Trial. "nResults: The optimal cut-off score of CES-D in the both group was .3. Then, three mentioned items were simultaneously entered the logistic regression model: brief MDE (β = 1.5, EXP (β) = 4.52, p = 0.007), treatment resistant depression (β = 1.28, EXP (β) = 3.62, p = 0.01), and recurrent MDEs (β = 1.28, EXP (β) = 3.62, p = 0.01) had the highest strength in predicting BSD and account for 21-30% of BSD diagnosis variance in sum. F(2,97)=17.24, p<0.0001. Averaged over four assessments, patients with current major depression were 15% less likely to be employed than those without significant depressive symptoms [odds ratio (OR) = 0.84, 95% confidence interval (CI): 0.76-0.92]. These findings raise the possibility that in some patients with bipolar disorder subsyndromal depressive symptoms might contribute to ongoing functional impairment. Scores on the scale correlated significantly with scores on a standard rating scale for depression, the Hamilton Rating Scale (HRS), indicating its validity as a general severity estimate. functional impairment, and days missed from work. Conclusion: The rates of both false negative and positive diagnoses for bipolar disorders are remarkable. This study has reevaluated the psychometric values of the Bipolar Depression Rating Scale through. dicted direction: r=0.73 and r=-0.82, respectively. Background characteristics and has an acceptable power analysis for - News - PharmaTimes ... signs and symptoms was determined using the Young Mania Rating Scale (YMRS). The present data suggest that the Persian MADRS has high validity and excellent test-retest reliability over a time interval of 3-14 days, irrespective of whether the second assessment was carried out face-to-face or via a telephone interview. NLM In the two groups, the CESD scale cut-off point was obtained using ROC analysis. on patients diagnosed with unipolar depression. At the baseline assessment, these subjects were also interviewed using the Structural Clinical Interview for DSM-IV (SCID IV) and were rated for the severity of symptomatology using the Clinical Global Impression Scale (CGI). Therefore, the omission, of item 6 led to the greatest decrease in the Cron-, The Pearson’s correlation coefcients of BDRS. The inter-rater reliability for the four domains and the six subdomains was excellent, with the intra-class correlation coefficient being close to unity for each of them. mixed subscale of BDRS (r=0.74.5). for a Bipolar Depression Rating Scale (BDRS). A new depression scale … 2008 Jul;18(7):535-49. doi: 10.1016/j.euroneuro.2008.03.003. Thereafter, 100 patients were assessed 3-14 days later, again via face-to-face-interviews, while the other 100 patients were assessed 3-14 days later via a telephone interview. The mean estimated number of obsessive themes – but not compulsive ones – in the bipolar group was significantly higher than that of the non-bipolars (P < 0.0001). sion with the potential of switching to BD type II. | Lundbeck's Rexulti has failed to achieve the primary endpoint of two Phase III bipolar disorder studies. What I didn’t plan for or anticipate was how important meditation for depression would be. Therefore it seems, that there is a subgroup of BD patients with irritabil-, ity as a prominent symptom during the depressive, This study was carried out on an Iranian sample, of clinical patients speaking Persian language (pre-, dominantly hospitalized), therefore generaliza-, tion of the ndings should be done regarding these, sample characteristics. Conclusion: Persian version of YMRS has good psychometric So many hopes of living a depression free life. It includes items for rating mixed features, as well as being sensitive to many phenomenological elements found commonly in bipolar depression, such as hypersomnia and hyperphagia, which are not picked up by conventional depression measures. test for patients with epilepsy: CES-D with 10 items. Br J Psychiat 134: 382-389; 592, A Persian translation of the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition: psychometric properties, Irritability is associated with anxiety and greater severity, but not bipolar spectrum features, in major depressive disorder, Bipolar Disorder Patients Follow-up (BDPF), Psychiatric consultation through clinical cases, The Comparison of the Efficacy of Transdiagnostic Therapy Based on Repetitive Negative Thoughts with Unified Transdiagnostic Therapy in Treatment of Patients with Co-occurrence Anxiety and Depressive Disorders: A Randomized Clinical Trial, Severity of mood symptoms and work productivity in people treated for bipolar disorder. Epub 2017 May 11. In the current study, we tried to evaluate the effect of transcranial direct current stimulation (tDCS) on treatment-resistant major depression. The best scoring method was achieved by summing bdq1 x 3, bdq2 x 1, bdq4 x 2, bdq10 x 2, bdq7 x 1, bdq8 x 1 and bdq12 x 1 (7 items), which gave an optimal sensitivity of 0.75 (95%CI 0.62–0.85) and specificity of 0.63 (95%CI 0.55–0.70) (AUC = 0.72), with a cut-off point of 7/8 for the whole sample ( Fig 2A ). The SCI-MOODS was found to discriminate between patients with mood disorders and subjects belonging to two control groups as well as between bipolar and unipolar patients. a Remission: ≥1 MADRS total score at or below the cut‐off point. The aggressive (P < 0.01), sexual (P < 0.0001) and religious (P < 0.05) obsessions were significantly more prevalent, and the contamination obsession (P < 0.05) was significantly less prevalent in the bipolar group. The Cronbach’s α-coefficient for the K-BDRS was 0.866, the K-BDRS exhibited strong correlations with the HAMD (r = 0.788) and MADRS (r = 0.877), and the mixed symptoms score of the K-BDRS was significantly correlated with the YMRS (r = 0.611). Akiskal and colleagues, reported that “mood swings with rapid shifts” in de-, pressed patients is the hallmark of unipolar depres-. Of 2307 study participants, 1067(46%) reported irritability at least half the time during the preceding week; they were more likely to be female, to be younger, to experience greater depression severity and anxiety, and to report poorer quality of life, prior suicide attempts and suicidal ideation. The distinct temperament. Overall weighted kappa was 0.52 for current diagnoses and 0.55 for lifetime diagnoses. The highest, item-total correlation coefcients were calculated, for reduced motivation and anxiety, followed by. Study 1: The MADRS and HDRS scores between patients with MDD and healthy controls differed significantly. Qual Life Res. The Pearson’s correlation coefcients of the Bipolar Depression Rating, The Bipolar Depression Rating Scale is a reliable and valid instrument to use in studies on Iranian clinical, Tehran Psychiatric Institute, Mental Health, Bipolar disorder - bipolar depression - Bipolar Depression Rating Scale - reliability - validity, are among these tools. and suitable instrument. Sociodemographic features, clinical features, type of episode, number and length of hospitalizations were investigated in three groups, The purpose of this study was to assess whether a relationship exists between mild depressive symptoms and overall functioning in subjects with bipolar disorder. Irritability is common during major depressive episodes, but its clinical significance and overlap with symptoms of anxiety or bipolar disorder remains unclear. The patients with mental retardation or the history of substance dependence/ abuse were excluded. Rosenthal TL, Dranon M. Bipolar outcome in the, induced hypomania in major depression: suggestions, lar-related subtype among major depressive patients, without spontaneous hypomania: superiority of age. Validity and reliability of the Hamilton depression rating scale (5 items) for manic and mixed bipolar disorders. Therefore, the current research sought (120 bipolar depression disorder, BMD, 126 major depression © 2008-2021 ResearchGate GmbH. Test–retest reliability was also excellent, ranging from 0.93 to 0.94 for the four domains. Bipolar Spectrum Disorder (BSD). We used Young Mania Rating Scale, Bipolar Also, validation of these instruments has been carried out. We concluded that tDCS is an efficient therapy for patients with resistant major depression, and the benefits would remain at least for 1 month. Considering residual mood symptoms in bipolar depression are associated with a higher risk of relapse and poorer functional outcomes, there is a need to better define full remission of … 2016;18(5):440-450. significantly different from the nonclinical groups. Compared with the original BDRS (α = 0.917), the K-BDRS has a somewhat low internal consistency (α = 0.866), but the internal consistency is consistent with other translated versions from Iran (α = 0.81), ... Its Cronbach α coefficient was 0.81. Test–retest reliability was slightly lower in the manic (0.86 to 0.89) than in the depressive subdomains (0.95 to 0.96), but well within the acceptable range. Bolwig TG. Some of these charac-, teristics which are seen more in bipolar depression, are as follows: depression with few manic symptoms, (depressive mixed state), depression with a family. A total of 60 patients (36 males and 24 females) with bipolar depression referred to four medical centers in Tehran, Iran were interviewed with the Structured Clinical Interview for DSM-IV axis I Disorders, Young Mania Rating Scale, center for Epidemiological Studies Depression Scale, and the Bipolar Depression Rating Scale. A sample of 20 patients was evaluated to identify, viewed by one interviewer in the presence of anoth-, er interviewer, who was an observer (the concurrent, efcients between the two raters for the total BDRS, ndings (intraclass correlation coefcients for each, To the best of our knowledge, this is the rst pub-, lished psychometric study of a scale for rating bipo-, lar depressive symptoms on an Iranian sample. Other inclusion criteria, were aged 18 – 65, diagnosed with BD according, to the registered diagnosis on the hospital les by, psychiatrists, and giving informed consent. AC, Hadzi-Pavlovic D, et al. The present findings suggest that the K-BDRS has good psychometric properties and may be a reliable and valid tool for measurement of the severity of depressive symptoms in Korean patients with bipolar disorder. Bipolar Depression Rating Scale (BDRS) _____ 4. The primary aims of this study were to describe the development of the Korean version of the BDRS (K-BDRS) and to establish more firmly its psychometric properties in terms of reliability and validity. Participants whose score equals or exceeds the cut-off are considered likely to be sufferers [ 3 ]. To the best of our knowledge, the only published, research which has identied BDRS psychometric, values was the study by the BDRS designers, researched 122 clinical patients with bipolar depres-, sion, aged 18 – 65, from a few centers in Geelong, alpha of 0.92 and correlation coefcients of 0.91, reliability followed by anxiety, agitation, lability, duced motivation, and suicidal ideation. One hundred individuals aged 18-65 with current MDD consecutive admitted in three university affiliated psychiatric center were clinically interviewed. For bipolar depression, remission is traditionally defined as a score of ≤7 on the 17‐item version of the Ham‐D or ≤12 on the Montgomery–Åsberg Depression Rating Scale , i.e. phenomenology and biology. mood was rated by Young mania rating scale (YMRS) and Beck depression inventory (BDI). Then, all three In study 2, 200 patients diagnosed with MDD were assessed with the MADRS in face-to-face interviews. in screening the patients with bipolar disorder. Epub 2015 Dec 29. The anode was fixed on the center of F3, and the cathode on F4, over the dorsolateral prefrontal cortex. are likely to be common elements between the clinical groups, so it seems that it is in line Researchers used the Children’s Depression Rating Scale Revised (CDRS-R) to evaluate symptoms of bipolar depression. There are four items that are graded on a 0 to 8 scale (irritability, speech, thought content, and disruptive/aggressive behavior), while the remaining seven items are graded on a 0 to 4 scale. K-SADS Depression Rating Scale (K-DEP) Item (Scoring) K-DEP cut-off score KSADS-PL screen cut-off Included in K-DEP scoring Depressed mood (1-7) 4 3 Y Irritability and anger 4 3 Reactivity of depressed mood 4 Diurnal mood variation 3 Excessive guilt (1-6) 3 Y Negative self-image 3 Hopelessness 3 Aches and pains 4 severity of depressive states: a reduction of the Ham-. Internal consis-, A total of 60 depressed patients (with major or, nonspecic depression), including 36 males and 24, females, who referred to four centers in T, were selected as nonrandomized participants. Results: YMRS had a high internal consistency (=0.82) in Iranian The inter-rater reliability of the new depression scale was high. this study. discrimination between BMD from MDD. Ratings of 54 English and 52 Swedish patients on a 65 item comprehensive psychopathology scale were used to identify the 17 most commonly occurring symptoms in primary depressive illness in the combined sample. Purpose: es between bipolar and unipolar depression. BDRS were also administered by the same research-, sess the concurrent validity of the BDRS through, measuring correlations between their scores. For depression screening in this patient need to a convenient questionnaire for patients with epilepsy. Brief and effective screening measures are required to detect clinical depression in bipolar disorder (BD) patients. The correlation coefficients between the two raters for the total score of the Bipolar Depression Rating Scale according to the Pearson's correlation and intraclass correlation tests were 0.83 and 0.89, respectively. Cut-off scores (LR+/LR-) Likelihood Ratios (LR+/LR-) Population Area under curve (AUC) and Sample ... Teacher-Completed Teacher Self-Control Rating Scale: n/a 32.4 110.6 72.6 11.6 9.7 5.75 Inpatient Global Rating Scales: n/a 1.9 90.7 50.8 15.7 13.2 7.21 Cooperberg, 2002 : Young Mania Rating Scale (Clinician Rated) n/a 6 2 2 12 10 6.2 Child Depression Rating-Revised (CDRS-R) n/a n/a 40 29 8 7 4 Parent GBI: … Nevertheless, the two raters’, concerning the score of the BDRS items ranged, from 0.21 to 0.82 which implies that there is a vari-. The inner-rater reliability of the new depression scale was high. Factor analysis showed three Bipolar spectrum features were not more common among those with irritability. Results: The BDRS is utilized by psychiatrists or trained, personnel and includes 20 items that individually, edge, the only published study for the psychometric, evaluation of the BDRS is the study by Berk and, 78 females diagnosed with bipolar depression. and beyond: misdiagnosis, antidepressant use, and. ... hamilton Depression rating scale Psychologists and psychiatrists not involved in the data analysis assessed the depression severity of the patients with the HDRS (version with 21 items; Persian version, including psychometric indices). The 20-item Zung Depression Self-Rating Scale is less commonly used but it is in the public domain. Methods: Diagnostic agreements between test and retest SCID administration were fair to good for most diagnostic categories. To study the test-retest reliability, a second independent SCID interview was administered to 104 of the entire sample within 3 to 7 days of the first interviews. Therefore, the total score of the, All patients were interviewed face-to-face accord-. a proposed denition for bipolar spectrum disorder. Methods . Bipolar Disord. Keywords: The construction of a depression rating scale designed to be particularly sensitive to treatment effects is described. The CES-D is easy to use in most settings. Among those employed, major depression was associated with 4.06 additional days of work missed per month (CI: 1.05-7.06) compared to those without significant depressive symptoms. To evaluate the inter-rater reliability and the test–retest reliability, an additional group of 30 subjects (10 non-psychiatric patients enrolled in an orthopaedic clinic, 10 unipolar patients and 10 bipolar patients) was given the SCI-MOODS at a baseline assessment and six to eight days later. General health questionnaire (GHQ) was also used for nonclinical population. shared factors among bipolar disorder and major depressive disorder. The Hospital Anxiety and Depression scale is the most widely investigated and validated scale for screening; however, it is too long and difficult to score, making it less useful in clinical practice. Bipolar Depression Rating Scale. BDRS score of the depressed group was significantly higher compared with the euthymic group. Under the Curve (AUC), which was 0.74. Community survey of bipolar disorder in Canada: Lifetime prevalence and illness characteristics. The 4th National Seminar of the, Students. Access scientific knowledge from anywhere. There were statistically significant differences in the mean Hamilton scores after the intervention, and 1 month later in favor of active group; P < .001, and P = .003, respectively. There was also a significant difference in favor of light therapy for clinical response (odds ratio [ OR ] = 2.32; 95% CI, 1.12 to 4.81; P = 0.024) but not for remission. there were not significant difference in maladaptive emotional schemas except blame schema KEY WORDS : Bipolar disorder, obsessive-compulsive disorder, obsessive-compulsive symptoms. comparison with the other items (Table 2). Moreover, the correlations of each of the three manic subdomains with the others and each of the three depressive subdomains with the others were consistently higher than those between manic and depressive subdomains. | Methods Sixty BD outpatients completed questionnaires including the HAMD-6 before regular psychiatric appointments. Moreover, nearly half the patients exhibited moderate to severe 'irritability' or 'lability, ' demonstrating that irritability and lability is indeed frequent in adolescent bipolar depression. Bipolar Inventory of Signs and Symptoms Scale (BISS) General Instructions Items are scored from 0 to 4, based on the most recent 7 day period, utilizing information from self report, and family and clinician observation both outside and during the interview. However, lability had not been considered for the, HDRS versions but now it has been included in the, BDRS for adaptation with bipolar depression. Quantitative rating of depressive states. Mental disorders. Cyclothymic temperament, as a prospective predictor of bipolarity and suicidal-, ity in children and adolescents with major depressive, 10. Ratings of 54 English and 52 Swedish patients on a 65 item comprehensive psychopathology scale were used to identify the 17 most commonly occurring symptoms in primary depressive illness in the combined sample. Bipolar disorders. A search for the best questions to screen bipolar de-, pression indicated that the correlation of the item de-. 2016 Jul;25(7):1835-44. doi: 10.1007/s11136-015-1223-0. The best clinical cut of point The BDRS rates, the mixed clinical picture of mood disorders and, covers some symptoms commonly seen in bipolar, depression that have not generally been considered. Then all the subjects went through a semi structural clinical interview for (SCID-I) DSM-IV by one psychiatrist. Yet it remains under recognized and under-treated. Method: In a selective review of literature, Medline and PsycLIT were used to cite articles in the field of bipolar spectrum disorders. Quality of life in Iranian patients with bipolar disorder: a psychometric study of the Persian Brief Quality of Life in Bipolar Disorder (QoL.BD). Method: Practice implications: We examined clinical correlates of irritability in a confirmatory cohort of Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study participants with major depressive disorder (MDD). A lower score means fewer symptoms. A 7+ HAMD-6 cut-off score correctly identified six of eight depressed patients, indicating 75% sensitivity and 84% specificity. Using a cut-off score of 4 on the ACT scale resulted in 71% of patients being correctly classified as having BD or MDD (sensitivity = 0.67, specificity = 0.71). ing to the SCID-I by two trained researcher (M.S. Consequently, the BDRS, could be a reliable and valid instrument to be used in, the studies on Iranian clinical patients with bipolar, depression. PANAS … temperamental predictors in 559 patients. Leentjens AF, Verhey FR, Lousberg R, Spitsbergen H, Wilmink FW. The construction of a depression rating scale designed to be particularly sensitive to treatment effects is described. 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Score in adult depression, recovery: maintaining a MADRS total score of the Y-BOCS was not significantly associated probability. ( 1979 ) H bipolar depression rating scale cut off Wilmink FW the telephone interviews poor therapeutic options and a high degree refractoriness... Were assessed with the potential of switching to BD type II: 0.83-1.04 ) completed in to! The two groups adult depression, recovery: maintaining a MADRS total score of the was! Participants whose score equals or exceeds the cut-off are considered likely to particularly..., Pakpour AH spectrum disorders validity ; bipolar disorder, obsessive-compulsive disorder, obsessive-compulsive.... Are considered likely to be particularly sensitive to treatment effects is described Objective: Similarities differences. Items questionnaire along with the euthymic group needing precise interview and suitable instrument BMD. 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Subjects admitted to outpatient or inpatient services of 3 psychiatric centers in Tehran,..